The PHA Depolymerase Engineering Database: A systematic analysis tool for the diverse family of polyhydroxyalkanoate (PHA) depolymerases |
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| Authors: | Michael Knoll Thomas M Hamm Florian Wagner Virginia Martinez and Jürgen Pleiss |
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| Institution: | (1) Institute of Technical Biochemistry, University of Stuttgart, Allmandring 31, 70569 Stuttgart, Germany;(2) Department of Molecular Microbiology, Centro de Investigaciones Biologicas Ramiro de Maeztu, 9, 28040 Madrid, Spain |
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| Abstract: | Background Polyhydroxyalkanoates (PHAs) can be degraded by many microorganisms using intra- or extracellular PHA depolymerases. PHA depolymerases
are very diverse in sequence and substrate specificity, but share a common α/β-hydrolase fold and a catalytic triad, which
is also found in other α/β-hydrolases. |
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