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Approaches for Integrated Risk Assessment
Authors:Wayne R. Munns  Robert Kroes  Gilman Veith  Glenn W. Suter II  Terri Damstra  Michael D. Waters
Affiliation:1. U.S. Environmental Protection Agency, Office of Research and Development, National Health and Environmental Effects Research Laboratory, 27 Tarzwell Drive, Narragansett, RI 02882, USA;2. Institute for Risk Assessment Sciences (IRAS), Utrecht University, PO Box 80176, NL-3508 TD Utrecht, The Netherlands;3. U.S. Environmental Protection Agency, Office of Research and Development, National Health and Environmental Effects Research Laboratory, NHEERL Building, MD-87, Research Triangle Park, NC 27711, USA;4. U.S. Environmental Protection Agency, Office of Research and Development, National Center for Environmental Assessment, 26 W. Martin L. King Drive, MC-117, Cincinnati, Ohio 45268, USA;5. World Health Organization, Interregional Research Unit, P.O. Box 12233, MD EC-10, Research Triangle Park, NC 27709, USA;6. U.S. Environmental Protection Agency, Office of Research and Development, National Health and Environmental Effects Research Laboratory, NHEERL Building, MD-51A, Research Triangle Park, NC 27711, USA
Abstract:Recognizing the need to enhance the effectiveness and efficiency of risk assessments globally, the World Health Organization's International Programme on Chemical Safety, the U.S. Environmental Protection Agency, the European Commission, and the Organization for Economic Cooperation and Development developed a collaborative partnership to foster integration of assessment approaches used to evaluate human health and ecological risks. The objectives of this effort included: improving understanding of the benefits of integration, identifying obstacles to the integration process, and engaging key agencies, organizations, and scientific societies to promote integration. A framework with supporting documentation was developed to describe an approach for integration. Four case studies were constructed to illustrate how integrated risk assessments might be conducted for chemical and nonchemical stressors. The concepts and approaches developed in the project were evaluated in an international workshop. The goal of this effort was international acceptance of guidance for integrated risk assessment.
Keywords:human health risk assessment  ecological risk assessment  integrated risk assessment
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