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Synthesis of new chiral cis-3-hydroxyazetidines and their application in diethylzinc addition to aldehydes |
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| Authors: | Zhang Zhanbin Li Min Zi Guofu |
| Affiliation: | Department of Chemistry, Beijing Normal University, Beijing, China. |
| Abstract: | A new series of chiral cis-3-hydroxyazetidines have been prepared from (R)-1-phenylethylamine. They have excellent catalytic activities and enantiomeric selectivities in asymmetric addition of diethylzinc to aromatic aldehydes. |
| Keywords: | cis‐3‐hydroxyazetidines chiral auxiliary synthesis application asymmetric diethylzinc addition reaction |
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