Amino acid sequence of the fetal chain of yak haemoglobin |
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| Authors: | R. Lalthantluanga G. Braunitzer |
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| Affiliation: | (1) Department of Biochemistry, North-Eastern Hill University, 793 014 Shillong, India;(2) Max-Planck-Institut für Biochemie, Am Klopferspitz 18A, 8033 Martinsried bei München, Federal Republic of Germany |
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| Abstract: | The amino acid sequence of the fetal chain of yak haemoglobin was determined. The sequence is the same as that of the fetal chain of bovine haemoglobin. Phenylalanine is present at position 12 of the helix A in the fetal chain while tryptophan is the amino acid at this position in theβ-chain of yak adult haemoglobin. This amino acid replacement may be responsible for the higher oxygen affinity of yak fetal haemoglobin than yak adult haemoglobin. |
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| Keywords: | Yak fetal haemoglobin amino acid sequence oxygen affinity |
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