Cannabis demasculinizes rats but is not estrogenic. |
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| Authors: | A B Okey G S Truant |
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| Affiliation: | Department of Biology University of Windsor Windsor, Ontario, CANADA, N9B 3P4 |
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| Abstract: | Cannabis resin (54% THC) caused dose-related decreases in the development of testis, prostate and seminal vesicles when administered in the diet to immature male rats. Bioassays and estrogen-receptor studies showed no estrogenic activity in cannabis resin. Demasculinazation and possible feminization by cannabis are not due to simple estrogen-like action on male tissues. |
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