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Cycleanine from Synclisia scabrida: conformational information from the 1H NMR spectrum at 300 MHz
Authors:Feodor Scheinmann  Eric F.V. Scriven  Osa N. Ogbeide
Affiliation:1. Department of Chemistry and Applied Chemistry, University of Salford, Salford, M5 4WT, U.K;2. Department of Chemistry, University of Benin, Benin City, Nigeria
Abstract:Cycleanine, a bisbenzylisoquinoline alkaloid, has been isolated from the roots of Synclisia scabrida. The 1H NMR spectrum at 300 MHz reveals that, in chloroform solution, cycleanine has a conformation whereby ring B partly shields ring C′ and ring C is similarly influenced by ring B′.
Keywords:Menispermaceae  alkaloids  cycleanine
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