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The alkaloids of Stephania sasakii: Structure of five new alkaloids
Authors:Jun-ichi Kunitomo  Yoshiko Murakami  Megumi Oshikata  Tetsuro Shingu  Michinori Akasu  Sheng-Teh Lu  Ih-Sheng Chen
Affiliation:1. Faculty of Pharmaceutical Sciences, Mukogawa Women''s University, 4-16, Edagawa-cho, Nishinomiya, Japan;2. School of Pharmacy, Kobe-gakuin University, Arise, Ikawadani-cho, Tarumi-ku, Kobe, Japan;3. Kaken Drug Co. Ltd., 3-37-10, Shimorenjaku, Mitaka City, Tokyo, Japan;4. School of Pharmacy, Kaohsiung Medical College, 100, Shih-Chuan 1st Road, San-Min District, Kaohsiung, Formosa Taiwan
Abstract:Five new alkaloids, dehydrocrebanine, 4,5-dioxodehydrocrebanine, stesakine, dehydrostesakine, bisaknadinine and four known alkaloids, lirodenine, lanuginosine, 1-tetrahydropalmatine, d-isocorydine with a few alkaloids of unknown structure were newly isolated from Stephania sasakii. The structures of the new alkaloids were determined from spectral data and chemical evidence.
Keywords:Menispermaceae  dehydrocrebanine  4,5-dioxodehydrocrebanine  bisaknadinine  stesakine  dehydrostesakine.
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