Comparison of Visceral Fat Measures with Cardiometabolic Risk Factors in Healthy Adults |
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| Authors: | Kyoungjune Pak Seung Hun Lee Jeong Gyu Lee Ju Won Seok In Joo Kim |
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| Affiliation: | 1Department of Nuclear Medicine and Biomedical Research Institute, Pusan National University Hospital, Busan, Korea;2Department of Family Medicine and Biomedical Research Institute, Pusan National University Hospital, Busan, Korea;3Department of Nuclear Medicine, Chung-Ang University College of Medicine, Seoul, Korea;The Ohio State University, UNITED STATES |
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| Abstract: | We aimed to evaluate the associations of visceral adiposity with cardiometabolic risk factors in normal subjects with integrated 18F-Fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT). A total of 58 normal subjects who underwent 18F-FDG PET/CT scan for cancer screening were included in this study. Volume and average Hounsfield unit (HU) of visceral adipose tissue (VAT) was measured from CT components of integrated PET/CT. Standardized uptake values (SUVmax) of liver, spleen, lumbar spine and ascending aorta (AA) were measured from PET components of integrated PET/CT. Body mass index (coefficient 78.25, p = 0.0259), glucose (37.62, p<0.0001), insulin (348.90, p = 0.0011), logarithmic transformation of homeostatic model assessment index-insulin resistance (-2118.37, p = 0.0007), and VAT HU (-134.99, p<0.0001) were independently associated with VAT volume. Glucose (0.1187, p = 0.0098) and VAT volume (-0.004, p<0.0001) were found to be associated with VAT HU. Both VAT volume and VAT HU of whole abdominal cavity is significantly associated with cardiometabolic risk factors. |
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