Electron microscopic examination of nuclear inclusions induced by Vinca alkaloids |
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| Authors: | Z. Somosy, O. Csuka,J. Sug r |
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| Affiliation: | Research Institute of Oncopathology, 1122 Budapest, Hungary |
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| Abstract: | Nuclear inclusions (filament bundles, crystalloid structures, “nuclear bodies”, tubular structures) in Ehrlich ascites cells induced by Vinca alkaloids were studied with a transmission electron microscope. The appearance of nuclear inclusions caused by VLB or DA-VCR may be attributed to the precipitation of tubulin, actin or some other acidic proteins. |
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