| 生物组织拉曼光谱数据的统计分析 |
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| 引用本文： | 李永增,冯尚源,林居强,陈冠楠,黄祖芳,谢树森,陈荣.生物组织拉曼光谱数据的统计分析[J].激光生物学报,2011,20(1):130-133,142. |
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| 作者姓名： | 李永增 冯尚源 林居强 陈冠楠 黄祖芳 谢树森 陈荣 |
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| 作者单位： | 福建师范大学激光与光电子技术研究所,福建省光子技术重点实验室,福建师范大学医学光电科学与技术教育部重点实验室,福建,福州,350007 |
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| 基金项目： | 国家自然科学基金，卫生部基金，福建省教育厅(B类)项目 |
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| 摘 要： | 拉曼光谱技术在生命科学领域已取得较为广泛的研究与应用,如何从低信噪比、质量差的拉曼光谱信号提取并充分利用谱图中所含信息,对光谱后续分析、样品的归类等至关重要.本文首先明确了生物组织拉曼光谱统计分析中几个重要的概念,进而对拉曼光谱数据的预处理,光谱分析研究中较为常用的几种多元统计方法进行了归纳、对比与分析.
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| 关 键 词： | 拉曼光谱 主成分分析 判别分析 聚类分析 生物组织 |
Statistical Analysis of Tissue Raman Spectroscopy |
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| LI Yong-zeng,FENG Shang-yuan,LIN Ju-qiang,CHEN Guan-nan,HUANG Zu-fang,XIE Shu-sen,CHEN Rong.Statistical Analysis of Tissue Raman Spectroscopy[J].ACTA Laser Biology Sinica,2011,20(1):130-133,142. |
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| Authors: | LI Yong-zeng FENG Shang-yuan LIN Ju-qiang CHEN Guan-nan HUANG Zu-fang XIE Shu-sen CHEN Rong |
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| Institution: | LI Yong-zeng,FENG Shang-yuan,LIN Ju-qiang,CHEN Guan-nan,HUANG Zu-fang,XIE Shu-sen,CHEN Rong~* (Institute of Laser and Optoelectronics Technology,Fujian Provincial Key Laboratory of Photonic Technology,Key Laboratory of Optoelectronic Science and Technology for Medicine,Ministry of Education,Fujian Normal University,Fuzhou 350007,Fujian,China) |
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| Abstract: | Raman spectroscopy has been entensively explored and become a very important tool in biomedical research. How to extract and fully utilize the information from low SNR spectra is very important to spectral analysis and sample classification.In this letter,some basic concepts in statistical analysis was demonstrated firstly,then pretreatment methods and several statistical analysis methods commonly used was described and reviewed. |
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| Keywords: | Raman spectroscopy principal component analysis discriminate analysis cluster analysis tissue |
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