Radical-Mediated Cyclization of A 6-Chloro-9-(2-Deoxy--d erythro-pent-1-enofuranosyl)-8-(2,2-dibromovinyl) purine |
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| Authors: | Atsushi Kittaka Naoki Yamada Hiromichi Tanaka Kazuo T. Nakamura Tadashi Miyasaka |
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| Affiliation: | School of Pharmaceutical Sciences , Showa University , 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142, Japan |
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| Abstract: | Abstract A vinyl radical generated from a 6-chloro-9-(2-deoxy--d eryrhro-pent-l-enofuranosyl)-8-(2,2-dibromovinyl) purine effected cyclization either at the 1′-or at the 2′-position. The result is discussed in comparison with our previous study of the corresponding uracil derivative. |
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