Acid-Catalyzed Photosubstitution of 5-Fluoro-1,3-Dimethyluracil with Substituted Benzenes |
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Authors: | Koh-ichi Seki Kazue Ohkura |
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Affiliation: | Faculty of Pharmaceutical Sciences , Higashi-Nippon-Gakuen University , Ishikari-Tobetsu, Hokkaido, 061-02, Japan |
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Abstract: | Abstract The substantial photosubstitution of 5-fluoro-1,3-dimethyluracil with substituted benzenes is first achieved by the addition of trifluoroacetic acid to the reaction mixture. The presence of protons is essential for the formation of 5-aryl-1,3-dimethyluracils. |
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