Synthesis of 2-S-dioxo Isosteres of Purine and Pyrimidine Nucleosides. III. Alkyl And Glycosyl Derivatives of Triazolo-and Thiadiazolothiadiazines. |
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| Authors: | B. Azmy P. Fernández-resa P. Goya R. Nieves C. Ochoa M. Stud |
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| Affiliation: | 1. Institute de Química Médica , Juan de la Cierva, 3, Madrid-6, Spain;2. Institute de Química Médica , Juan de la Cierva, 3, Madrid-6, Spain;3. Institute de Química Orgánica General , Juan de la Cierva, 3, Madrid-6, Spain |
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| Abstract: | Abstract Synthesis of methyl, glucosyl and ribosyl derivatives of 7-amino-2H, 4H-[1, 2, 3]triazolo [4, 5-c] [1, 2, 6] thiadiazine 5, 5-dioxide (1a) and 7-amino-4H- [1, 2, 5] thiadiazolo [3, 4-c][1, 2, 6] thiadiazine 5, 5-dioxide (2a) is described. The structures of the glycosyl derivatives are discussed on the basis of their PMR- and UV-spectroscopic data. |
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