Amino Acid Nucleic Acids: Synthesis and Hybridization Properties of a Novel Class of Antisense Oligonucleotides |
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| Authors: | Kanda S. Ramasamy Wilfried Seifert |
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| Affiliation: | Research Division , ICN Pharmaceuticals, Inc. , 3300 Hyland Avenue, Costa Mesa, CA, 92626 |
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| Abstract: | Abstract Oligonucleotides containing novel phoshoramidite 12 were synthesized and studied for their hybridization properties for the first time. Interestingly, these modified oligonucleotides showed a remarkable resistance to exonuclease. |
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