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Influence of Phospholipase A2-Prostaglawdin System Linked to A1 Adexosine Becepmb on Protein Kinase C Activity of Cultubed Glial Cells
Authors:R. Ciccarelli  M. Di Muzio  P. Di Iorio  P. Ballerini  F. Caciagli
Affiliation:Institute of Neuroscience, Chair of Pharmacology. University of Chieti. Medical School , Via dei Vestini 31, 66013, Chieti, Italy
Abstract:Abstract

In cultured astrocytes phospholipase A2 seems to be functionally linked to G1 protein of A1 adenosine receptors. Phospholipase A2 inhibition and A1-linked G1 protein inactivation resulted in purine release increase due to protein kinase C activation.
Keywords:
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