Influence of Phospholipase A2-Prostaglawdin System Linked to A1 Adexosine Becepmb on Protein Kinase C Activity of Cultubed Glial Cells |
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Authors: | R. Ciccarelli M. Di Muzio P. Di Iorio P. Ballerini F. Caciagli |
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Affiliation: | Institute of Neuroscience, Chair of Pharmacology. University of Chieti. Medical School , Via dei Vestini 31, 66013, Chieti, Italy |
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Abstract: | Abstract In cultured astrocytes phospholipase A2 seems to be functionally linked to G1 protein of A1 adenosine receptors. Phospholipase A2 inhibition and A1-linked G1 protein inactivation resulted in purine release increase due to protein kinase C activation. |
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