Synthesis of Reagents for Fluorescence-Tagging of DNA |
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Authors: | George L Trainor Frank W Hobbs Anthony J Cocuzza Pat N Confalone |
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Institution: | Central Research and Development Department , E. I. Dupont de Nemours and Company , Wilmington, DE, 19880-0328 |
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Abstract: | Abstract A general route for the synthesis of alkynylamino nucleoside triphosphates is described. These nucleosides can be selectively coupled through the alkynylamino group to a variety of reporter groups and used to enzymatically label DNA. |
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