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Synthesis And Antiviral Evaluation Of 2′,3′-Secothymidine Analogs of ddT and AZT |
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| Authors: | Annie-Fransoise Maggio Valerie Boyer Anne-Marie Aubertin Georges Obert André Kirn Jean-Louis Imbach |
| Institution: | 1. Laboratoire de Chimie Bio-Organique, UMR 112 Synthélabo-CNRS-USTL , Université II Sciences et Techniques du Languedoc , Place Eugène Bataillon, 34095, Montpellier-Cédex 5, France;2. U. 74 de l'INSERM, Laboratoire de Virologie de la Faculté de Médecine , Université Louis-Pasteur , 3 rue Koeberlé, 67000, Strasbourg, France |
| Abstract: | Abstract 2′,3′-Secothymidine derivatives related to AZT and ddT have been synthesized and evaluated for their activity against HIV-1 and various DNA and RNA viruses. These acyclic nucleosides exhibited no antiviral activities. |
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