Differential Sensitivities of Normal and Malignant Murine Lymphocytes to Purine Nucleosides |
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| Authors: | J. Arly Nelson Ellen R. Richie Osama Kandil Elena Vidale Bih Fang Pan |
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| Affiliation: | Departments of Experimental Pediatrics , The University of Texas M. D. Anderson Cancer Center , 1515 Holcombe Boulevard Houston, Texas, 77030 |
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| Abstract: | Abstract Inherited human immunodeficiences associated with loss of adenosine deaminase or purine nucleoside phosphorylase are thought to result from accumulation of the nucleoside substrates. This work attempts to identify lymphocyte subpopulations that are uniquely-sensitive to the endogenous substrates or their analogs. |
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