Recent Progress in Oligoribonucleotide Synthesis |
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| Authors: | Magdalena Pfister Silke Farkas Ramamurthy Charubala Wolfgang Pfleiderer |
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| Affiliation: | Fakult?t für Chemie , Universit?t Konstanz , Postfach 5560, 0-7750, Konstanz |
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| Abstract: | Abstract The usefulness of the p-nitrophenylethylsulfonyl (NPES) group for 2′-OH protection in oligoribonucleotide synthesis is further investigated. The difficulties of uridine protection are discussed and the p-cyanophenylethyl (CPE) group introduced as a versatile new 04-blocking group. |
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