Quantitative Analysis of Orotic Acid in Urine by RP-HPLC |
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Authors: | B. Giordano A. T. Cracco V. Ferrari N. Dussini L. Chiandetti F. Zacchello |
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Affiliation: | Department of Pediatrics , University of Padova , Italy |
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Abstract: | Abstract we describe a new RP-HPLC assay to measure orotate concentration in urine. The method is rapid, sensitive and precise. It is particularly suitable for the diagnosis of inherited metabolic diseases and deranged orotate metabolism. |
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