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Quantitative One Step Derivatization of Oligonucleotides by a Fluorescent Label Through Abasic Site Formation |
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| Authors: | Didier Boturyn Eric Defrancq Veacute; onique Ducros Catherine Fontaine Jean Lhomme |
| Institution: | 1. LEDSS , UMR 5616, UniversitC Joseph Fourier, - Grenoble 1 , BP 53, 38041, GRENOBLE CEDEX 9, FRANCE;2. Laboratoire de BIOCHIMIE, C-CHU Grenoble , BP 217, 38043, GRENOBLE CEDEX 9 |
| Abstract: | Abstract Reaction of abasic site-containing oligonucleotides with an oxyamino fluorescent label is described. The reaction represents an efficient method to functionalize oligonucleotides at preselected positions. |
| Keywords: | |