Synthesis of Uridylyl (3′-5′) Uridine Derivatives Containing 5-(Methylamino-Methyl) Uridine as A Modified Nucleoside Found from E. COLI Minor tRNAArg |
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| Authors: | Mitsuo Sekine Kouji Seio Takahiko Satoh Kensaku Sakamoto Shigeyuki Yokoyama |
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| Institution: | 1. Department of Life Science , Faculty of Bioscience and Biotechnology Tokyo Institute of Technology, Nagatsuta , Midoriku, Yokohama, 227, Japan;2. Department of Biophysics and Biochemistry , Faculty of Science, the University of Tokyo , Hongo, Bunnkyo-ku, Tokyo, 113, Japan |
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| Abstract: | Abstract 5-(Methylaminomethyl)uridine-containing uridylyl (3′-5′) uridine derivatives (14, 26, and 29), which were the original and modified sequences corresponding to the first letter (position 34) and the 5′-upper ribonucleoside (position 33) in the anticodon loop of minor tRNAArg, have been synthesized via 5-(methylaminomethyl)uridine derivatives (4 and 24). |
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