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Comparison of Physicochemical and Biological Properties of (o-Carboran-1-YL)methylphosphonate and Methylphosphonate Oligonucleotides |
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| Authors: | Zbipniew J Lesnikowski Robert M Lloyd Jr Raymond F Schinazi |
| Institution: | 1. Veterans Affairs Medical Center and Georgia Research Center for AIDS and HIV Infections , Medical Research 151, Decatur, Georgia , 30033-4004;2. Laboratory of Biochemical Pharmacology, Department of Pediatrics , Emory University School of Medicine , Atlanta, Georgia , 30322 |
| Abstract: | Abstract (o-Carboran-1-yl)methylphosphonate (CBMP) oligonucleotides demonstrate advantages in their physicochemical and biological characteristics over the corresponding methylphosphonate oligonucleotides. |
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