Methylation of a Mesoionic Tricyclic Nucleoside Related to Wyosine |
| |
| Authors: | Jerzy Boryski Bozenna Golankiewicz |
| |
| Affiliation: | Institute of Bioorganic Chemistry Polish Academy of Sciences , Noskowskiego 12/14, 61-70, Poznan, Poland |
| |
| Abstract: | Abstract 4-Desmethylwyosine/2/, a formal precursor of a hyper-modified nucleoside wyosine /1/ was modified by N-1 benzylation. Mesoionic character of the resulting compound 3b, despite the similarities to wyosine in electron density distribution as shown by 13c NMR, does not enforce the change of methylation direction towards the desired N-4 position. |
| |
| Keywords: | |
|
|
