Synthesis of 1,5-Anhydrohexitol Nucleosides as Mimics of AZT,D4T and DDC |
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| Authors: | Ilse Verheggen Arthur Van Aerschot Jef Rozenski Gerard Janssen Erik De Clercq Piet Herdewijn |
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| Affiliation: | 1. Laboratory of Medicinal Chemistry, Rega Institute for Medical Research , K. U. Leuven, Minderbroedersstraat 10, B-3000 , Leuven , Belgium;2. Laboratory of Experimental Chemotherapy, Rega Institute for Medical Research , K. U. Leuven, Minderbroedersstraat 10, B-3000 , Leuven , Belgium |
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| Abstract: | Abstract 1,5-Anhydrohexitol congeners of AZT, D4T and DDC were synthesized. These compounds did not show anti-HIV activity. |
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