Preparative Syntheses of Guanylate-Rich Oligonucleotides Using the Phosphotriester Method in Solution |
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| Authors: | H Schott R Semmler K Cloß |
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| Institution: | Institut für Organische Chemie der Universit?t Tübingen Auf der Morgenstelle , 18 D-7400, Tübingen |
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| Abstract: | Abstract The guanylate-rich fragments: 150 mg d(G4T4), 180 mg d(T4G4), 350 mg d(T4G4T4), 30 mg d(G4T4G4), 85 mg d(T4G4T4G4)were synthesized using the triester method. By enzymatic ligation of aliquots the 36mer d(G4T4G4T4G4T4G4T4G4) is obtained. |
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