Ring Opening Reaction of Pyrazolo[3,4-c]Maleimide Nucleosides |
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Authors: | Sungjoong Kim Wooyeon Won Yonghan Kang |
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Affiliation: | Department of Chemistq , Hanyang Universiw , Ansan, Kyungki-Do, 425-791, South Korea |
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Abstract: | Abstract Synthesis of pyrazolo[3,4-c]maleimide nucleosides was attempted, but ring opening reaction of the maleimide part was observed during ammonolysis of sugar-protected pyrazolo[3,4-c]maleimide nucleosides. The isolated pyrazole nucleosides were characterized by NMR spectra and X-ray analysis. |
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