Studies Toward Synthesis of C2-Substituted Adenosines: An Efficient Synthesis of 2-(Phenylamino)Adenosine [CV-1808] |
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Authors: | Bharat K Trivedi |
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Institution: | Parke-Davis Pharmaceutical Research Warner/Lambert Company, Department of Chemistry , Ann Arbor, Michigan, 48105 |
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Abstract: | Abstract In this paper we report general and highly efficient synthetic routes to certain C2,N6-disubstituted adenosines including an efficient synthesis of 2-(phenylamino)adenosine CV-1808, a highly A2 receptor selective adenosine agonist] originally developed as an antianginal agent. |
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