Photo-Induced P-Methylbenzylation of 1,3-Dimethylthymine and 1, 3-Dimethyluracil in the Presence of Trifluoroacetic Acid |
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| Authors: | Koh-ichi Seki Kazue Ohkura |
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| Affiliation: | Faculty of Pharmaceutical Sciences, Higashi-Nippon-Gakuen University , Ishikari-Tobetsu, Hokkaido, 061-02 |
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| Abstract: | Abstract Photolysis of a solution of a pyrimidine (i. e., 1, 3-dimethylthymine and 1, 3-dimethyluracil) in p-xylene in the presence of trifluoroacetic acid afforded mainly the 5, 6-dihydropyrimidine derivative together with the 5-p-methylbenzylated product and the 6-isomer as well. It is suggested that the first two products result from the C6-protonated pyrimidine electron adduct (III), while the 6-isomer is derived from the O4-protonated isomer (II). |
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