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Fluorescence Properties of Y-Nucleoside Derivatives |
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| Authors: | T. M. Nordlund R. Rigler C. Glemarec J.-C. Wu H. Bazin G. Remaud |
| Affiliation: | 1. Dept. of Medical Biophysics , Karolinska Institute , S-104 01, Stockholm, Sweden;2. Dept. of Biophysics, Dept. of Physics &3. Astronomy, Laboratory for Laser Energetics , University of Rochester , Rochester, NY, 14642, USA;4. Dept. of Medical Biophysics , Karolinska Institute , S-104 01, Stockholm, Sweden;5. Dept. of Bioorganic Chemistry , Box 581, Biomedical Center, University of Uppsala , S-751 23, Uppsala, Sweden |
| Abstract: | Abstract Modified-base and modified N3-(β-D_-ribofuranoside) derivatives of the Y base exhibit subnanosecond fluorescence decays. Attachment of groups to the “unnatural” N1 base position produces compounds showing dominant 7 - 10 ns decays. These spectral properties have been compared with those of the free Y base and suggest that the free Y base exists mainly as the N1-H tautomer. |
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