Improved Synthesis and Cytostatic Activity of 1-Deazaadenosine |
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| Authors: | Gloria Cristalli Palmarisa Franchetti Mario Grifantini Sauro Vittori Teresa Bordoni Cristina Geroni |
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| Affiliation: | 1. Dipartimento di Scienze Chimiche , Università di Camerino , 62032, Camerino;2. Farmltalia-Carlo Erba , Milano, Italy |
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| Abstract: | Abstract A more convenient synthetic route to 1-deazaadeno-sine starting from 7-nitroimidazo[4,5-b]pyridine 4-oxide is reported. 1-Deazaadenosine showed a good cytostatic activity in vitro. |
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