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Ligand Binding to A1 Adenosine Receptors is Influenced by Protonation |
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| Authors: | Edmund Hoppe Martin Reddington |
| Institution: | Department of Neuromorphology , Max Planck Institute for Psychiatry , Am Klopferspitz, 18a, FRG |
| Abstract: | Abstract Studies on the pH dependence of ligand binding to A1 adenosine receptors revealed that protonation of a histidine residue in the binding pocket is accompanied by high affinity agonist binding. |
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