Proton/sodium ion antiport in Escherichia coli |
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Authors: | Ian C West and Peter Mitchell |
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Institution: | Glynn Research Laboratories, Bodmin, Cornwall PL30 4AU, U.K. |
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Abstract: | In anaerobic suspensions of Escherichia coli, after H(+) ions have been translocated outwards across the plasma membrane by a respiratory pulse, re-equilibration is catalysed by Na(+). The sudden addition of a Na(+) salt causes the effective outward translocation of H(+) by an electroneutral process. We conclude that the plasma membrane of E. coli contains a Na(+)/H(+) antiport system that normally translocates Na(+) outwards under the influence of an inwardly directed H(+)-activity gradient. |
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