Effect of carbostimulin on the concentration of tricarboxylic cycle metabolites, oxidative processes and antibody biosynthesis in the rat

Carbostimulin is studied for the effect it exerts on indices of the acid-base equilibrium of blood, content of certain tricarboxylic-cycle metabolites and free amino acids and formation of antibodies in rats. It is established that carbostimulin feeding increases the total carbon dioxide, pyruvate and lactate concentration in blood, the content of ammonium, glutamine and certain free amino acids being decreased. Oxidation processes in the liver mitochondria and biosynthesis of antibodies in experimental animals are shown to be more intensive than in the control ones.