The search for the ideal biocatalyst. |
| |
Authors: | Stephanie G Burton Don A Cowan John M Woodley |
| |
Affiliation: | Department of Chemical Engineering, University of Cape Town, Cape Town, South Africa. |
| |
Abstract: | While the use of enzymes as biocatalysts to assist in the industrial manufacture of fine chemicals and pharmaceuticals has enormous potential, application is frequently limited by evolution-led catalyst traits. The advent of designer biocatalysts, produced by informed selection and mutation through recombinant DNA technology, enables production of process-compatible enzymes. However, to fully realize the potential of designer enzymes in industrial applications, it will be necessary to tailor catalyst properties so that they are optimal not only for a given reaction but also in the context of the industrial process in which the enzyme is applied. |
| |
Keywords: | |
|
|