Production of artemisinin by hairy root cultures of Artemisia annua L |
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Authors: | C.Z. Liu Y.C. Wang F. Ouyang H.C. Ye G.F. Li |
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Affiliation: | (1) State Key Laboratory of Biochemical Engineering , Institute of Chemical Metallurgy, Chinese, Academy of Sciences, Beijing, 100080, China;(2) Institute of Botany , Chinese Academy of Sciences, Beijing, 100093, China |
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Abstract: | Using a combination of sucrose (70 g/L), nitrate (30 mM), inorganic phosphate (1.5 mM), gibberellic acid (5 mg/L) and the ratio of N (NH ) to N - (NO ) (1:5), artemisinin production was increased to 550 mg/L when the cultures of Artemisia annua L hairy root were elicited with a homogenate of Aspergillus oryzae. |
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