Rapid chromosome territory relocation by nuclear motor activity in response to serum removal in primary human fibroblasts |
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| Authors: | Ishita S Mehta Manelle Amira Amanda J Harvey Joanna M Bridger |
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| Affiliation: | (1) Centre for Cell and Chromosome Biology, Division of Biosciences, School of Health Sciences and Social Care, Brunel University, Kingston Lane, Uxbridge, UB8 3PH, UK;(2) Division of Biosciences, Brunel Institute for Cancer Genetics and Pharmacogenomics, School of Health Sciences and Social Care, Brunel University, Kingston Lane, Uxbridge, UB8 3PH, UK |
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| Abstract: | Background Radial chromosome positioning in interphase nuclei is nonrandom and can alter according to developmental, differentiation, proliferation, or disease status. However, it is not yet clear when and how chromosome repositioning is elicited. |
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