Meroterpenoids from the fruiting bodies of higher fungus Ganoderma resinaceum |
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| Affiliation: | 1. Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, 16 Nanxiaojie, Dongzhimennei Ave, Beijing 100700, China;2. Shandong Analysis and Test Center, Shandong Academy of Sciences, 19 Keyuan Street, Jinan, Shandong 250014, China;1. CNRS, Institut de Chimie des Substances Naturelles, UPR 2301, 1 avenue de la Terrasse, 91198 Gif-sur-Yvette, France;2. Sorbonne Universités, UPMC Univ. Paris 06, CNRS, Laboratoire de Biodiversité et Biotechnologies Microbiennes (LBBM), Observatoire Océanologique, 66650 Banyuls/Mer, France;1. Department of Pharmacy, Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing 210008, Jiangsu Province, China;2. North China University of Science and Technology,Tangshan, 063210, Hebei Province, China;3. Department of hand and foot surgery, Tengzhou Center People''s Hospital, Tengzhou 277500, Shandong Province, China;4. Department of Pharmacy, the First Affiliated Hospital of Nanchang University, Nanchang 330006, Jiangxi Province, China;1. Instrument Centre, Department of Chemistry, University of Turku, FI-20014, Turku, Finland;2. Molecular Plant Biology, Department of Biochemistry, University of Turku, FI-20014 Turku, Finland;3. Food Chemistry and Food Development, Department of Biochemistry, University of Turku, FI-20014 Turku, Finland;1. School of Pharmaceutical Sciences, Shenzhen University Health Science Center, Shenzhen 518060, PR China;2. State Key Laboratory of Phytochemistry and Plant Resources in West China, Key Laboratory for Plant Diversity and Biogeography of East Asia, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, PR China;3. Biotechnology Research Center, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan;1. Guangdong Key Laboratory for Genome Stability & Disease Prevention, School of Pharmaceutical Sciences, School of Medicine, Shenzhen University Health Science Center, Shenzhen 518060, People’s Republic of China;2. School of Pharmacy, Guangxi University of Chinese Medicine, Nanning 530001, People’s Republic of China |
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| Abstract: | Phytochemical investigation on the fruiting bodies of Ganoderma resinaceum led to the isolation of five new meroterpenoids, namely ganoresinains A–E (1–5), and four known analogues (6–9). The new compounds were identified by extensive analyses of spectroscopic data (NMR, MS, UV, and IR) and comparison with the literature data. Compound 1 and 6 were isolated as enantiomeric mixture, which were separated over analytical chiral HPLC chromatography. Compounds 6–9 were isolated from G. resinaceum for the first time. |
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| Keywords: | Meroterpenoid Ganoresinains A–E Enantiomer |
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