Steroidal saponins with cytotoxic activities from the rhizomes of Anemarrhena asphodeloids Bge. |
| |
| Institution: | 1. Institute of Bioproduct Development, Universiti Teknologi Malaysia, Johor Bahru, Johor, Malaysia;2. Department of Bioprocess and Polymer Engineering, School of Chemical & Energy Engineering, Faculty of Engineering, Universiti Teknologi Malaysia, Johor, Malaysia |
| |
| Abstract: | Two new steroidal saponins, named timosaponin R (1) and S (2), together with seven known compounds (3-9) were isolated from the rhizomes of Anemarrhena asphodeloides Bge. Their structures were elucidated on the basis of NMR spectroscopy and mass spectrometry. All the compounds were evaluated for cytotoxic activities against the four human cancer cell lines MCF7, SW480, HepG2 and SGC7901 in vitro. Compounds 7-9 showed moderate activities against all the cell lines. |
| |
| Keywords: | Steroidal glycoside Cytotoxic activity |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
