Furan derivatives from Lannea kerstingii |
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| Affiliation: | 1. Department of Chemistry, Faculty of Science, University of Dschang, P.O. Box 67, Dschang, Cameroon;2. Department of Chemistry, Organic and Bioorganic Chemistry, Bielefeld University, P.O. Box 100131, 33501 Bielefeld, Germany;1. Department of Analytical Chemistry, University of Granada, Avda. Fuentenueva s/n, 18071 Granada, Spain;2. Research and Development of Functional Food Centre (CIDAF), PTS Granada, Avda. Del Conocimiento s/n, Edificio BioRegión, 18016 Granada, Spain;3. Research and Development of Functional Olive Oil Department, Aceites Maeva S.L., Avda. Incar, s/n, 18130, Escúzar, Granada, Spain;4. Catholic University of San Antonio, Los Jerónimos campus 135, 30107 Guadalupe, Murcia, Spain;1. Institute of Environmental Research (INFU), Department of Chemistry and Chemical Biology, TU Dortmund, Otto-Hahn-Straße 6, 44227, Dortmund, Germany;2. Department of Microbial Drugs, Helmholtz Centre for Infection Research, 38124, Braunschweig, Germany;3. German Centre for Infection Research (DZIF), Partner Site Hannover-Braunschweig, 38124, Braunschweig, Germany;4. Department of Chemistry, Faculty of Sciences, Egerton University, P.O. Box 536, 20115, Egerton, Kenya;5. Department of Chemistry, Addis Ababa University, P.O. Box 33658, Addis Ababa, Ethiopia |
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| Abstract: | Two new furan derivatives, lannefuran A (1) and lannefuran B (2) were isolated from the stem bark extract of Lannea kerstingii Engl. & K. Krause together with five known compounds, namely: taraxerol, stigmast-4-en-3-one, monoglyceride of hexacosanoic acid, β-sitosterol and its glucoside. Their structures were determined by means of 1D and 2D NMR, IR, and HR–EI–MS spectra and comparison with the data of known analogues reported in the literature. Lannefuran A (1) exhibited very low antiplasmodial activity against Plasmodium falciparum 3D7. |
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| Keywords: | Anarcadiaceae Bifuran |
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