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Three terpenoid glycosides of Centipeda minima
Affiliation:1. Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, Acad. G. Bonchev Str., bl. 9, 1113 Sofia, Bulgaria;2. Institute of Biodiversity and Ecosystem Research, Bulgarian Academy of Sciences, 2 Gagarin Str., 1113 Sofia, Bulgaria;1. Faculty of Chemistry and Chemical Engineering, Yunnan Normal University, Kunming 650050, China;2. College of Pharmaceutical Science, Yunnan University of Traditional Chinese Medicine, Kunming 650050, China;1. Pharmacognosy Department, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia;2. Pharmacognosy Department, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt;3. Chemistry Department, Science College, Princess Noura bint Abdul Rahman University, Riyadh 11671, Saudi Arabia;4. Pharmacognosy Department, College of Pharmacy, Sattam Bin Abdulaziz University, Al-kharj 11942, Saudi Arabia;1. The Experimental Forest Management Office, National Chung Hsing University, Taichung 402, Taiwan;2. Department of Nursing, Hungkuang University, Taichung 443, Taiwan;3. Department of Biotechnology, Hungkuang University, Taichung 443, Taiwan;4. Department of Forestry, National Chung Hsiung University, Taichung 402, Taiwan;5. Graduate Institute of Pharmaceutical Science and Technology, Central Taiwan University of Science University, Taichung 406, Taiwan;6. Department of Cosmeceutics, China Medical University, Taichung 404, Taiwan;7. Department of Health and Nutrition Biotechnology, Asia University, Taichung 413, Taiwan;8. Department of Chemistry, National Taiwan University, Taipei 106, Taiwan;9. Department of Chinese Pharmaceutical Sciences and Chinese Medicine Resources, China Medical University, Taichung 404, Taiwan;10. Department of Biotechnology, Asia University, Taichung 413, Taiwan
Abstract:From the n-BuOH-soluble extract of the whole plant of Centipeda minima (Asteraceae), the investigation on chemical constituents led to the isolation of three new compounds including 3′-desulphatedatractyloside (1), 15-O-[α-l-rhamnosyl-(1→2)-β-d-glucosyl]grandiflorolic acid (2), and 2α-hydroxylemmonin C (3), along with five known compounds (4–8). Their structures were elucidated on the basis of the NMR spectroscopic analysis.
Keywords:Asteraceae  Terpenoid glycoside  Sesquiterpene lactone
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