Isoflavonoids and norneolignan from Caragana changduensis |
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| Institution: | 1. School of Biotechnology and Health Sciences, Wuyi University, Jiangmen 529020, China;2. International Healthcare Innovation Institute (Jiangmen), Jiangmen 529040, China;1. State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin 300350, China;2. Key Laboratory for Green Processing of Chemical Engineering of Xinjiang Bingtuan, School of Chemistry and Chemical Engineering, Shihezi University, Shihezi 832003, China;3. College of Chemistry and Environmental Sciences, Laboratory of Xinjiang Native Medicinal and Edible Plant Resources Chemistry, Kashgar University, Kashgar 844000, China;4. School of Medicine, Nankai University, Tianjin 300071, China;5. Kansei Fukushi Research Institute, Tohoku Fukushi University, Sendai 989-3201, Japan;6. Department of Biosystems and Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul 136-713, Republic of Korea;1. Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou 225001, China;2. Jiangsu Key laboratory of integrated traditional Chinese and Western Medicine for prevention and treatment of Senile Diseases, Yangzhou University, Yangzhou 225001, China;3. The Key Laboratory of Syndrome Differentiation and Treatment of Gastric Cancer of the State Administration of Traditional Chinese Medicine, Yangzhou 225001, China;4. Jiangsu Co-Innovation Center for the Prevention and Control of Important Animal Infectious Diseases and Zoonoses, College of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China;1. State Key Laboratory of Phytochemistry and Plant Resources in West China, and Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China;2. University of Chinese Academy of Sciences, Beijing 100049, China;3. Yunnan Characteristic Plant Extraction Laboratory, Kunming 650106, China |
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| Abstract: | Two new isoflavonoids, named 6,7,2′-trihydroxy-4′-methoxyisoflavone (1), 7,3′-dimethoxy-5′-hydroxyisoflavone (2), one new norneolignan, named (8S)-2,4-dihydroxy-8-hydroxymethyl-4′-methoxydeoxybenzoin (3); together with six known compounds, methyl 4-hydroxylbenzoate (4), ethyl 4-hydroxybenzoate (5), piceatannol (6), cararosin A (7), 2,4-dihydroxybenzoate (8), and 6,7,4′-trihydroxyisoflavone (9) were isolated from the red heartwood in the rhizomes of Caragana changduensis by using chromatographic methods Their structures were determined by extensive spectroscopic analysis and comparison of their spectral data with previous reported data. |
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| Keywords: | Isoflavonoids Norneolignan |
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