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Chemical constituents of the root bark of Erythrina droogmansiana
Institution:1. Bio-Evaluation Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju 363-883, Republic of Korea;2. Entomology Program, Department of Agricultural Biotechnology, Seoul National University, Seoul 151-921, Republic of Korea;3. Department of Biology Education, Gyeongsang National University, Jinju 660-701, Republic of Korea;4. R&D Headquarters, Nongwoo Bio Co., Yeoju 469-885, Republic of Korea
Abstract:Two new compounds namely 7,4′-dihydroxy-2′-methoxy-3′-(3-methylbut-2-enyl)isoflavanone (1) and 5,7,3′-trihydroxy-8-(3-methylbut-2-enyl)-6′′,6′′-dimethylpyrano(2′′,3′′:4′,5′)]isoflavone (4) were isolated from the root bark of Erythrina droogmansiana together with eight known compounds. Their structures were elucidated on the basis of spectroscopic analyses (1D- and 2D-NMR and ESI-HRMS) and by comparison with literature data. In addition, the correct 13C NMR of 5,7,2′,4′-tertahydroxy-8,5′-di-(3-metylbut-2-enyl)isoflavone (6) was assigned. The DPPH free radical scavenging properties of the isolated compounds were evaluated. Compounds 4–7 showed weak to moderate DPPH free radical scavenging activities.
Keywords:Leguminosae  Isoflavanone  Erydroogmansin A and B  NMR
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