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A window on cyclitols: Characterization and analytics of inositols
Institution:1. School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China;2. School of Pharmacy, Shihezi University Shihezi 832002, China;3. Mongolian Medicine College of Pharmacy, Inner Mongolia University for the Nationalities, Tongliao 028043, China;4. School of life science and Biotechnology, Shenyang Pharmaceutical University, Shenyang 110016, China;1. National Institute of Health Sciences, Setagaya, Tokyo 158-8501, Japan;2. Faculty of Sciences, Toho University, Funabashi, Chiba 274-8510, Japan;3. Faculty of Pharmaceutical Sciences, Toho University, Funabashi, Chiba 274-8510, Japan
Abstract:Cyclitols are cycloalkanes with one hydroxyl group on each of three or more ring atoms, also called cycloalkane polyols or sugar alcohol which attract attention since they have numerous pharmaceutical properties and are widespread in the plants. Inositols are important cyclitols, which constitute a group of naturally occurring polyhydric alcohols and some isomers of this group can be commonly found in most plants, provided adequate methods of detection are employed. This review presents plant containing cyclitols, with emphasis put on their pharmaceutical properties. The text focuses on sample preparation, extraction and purification and on analysis of cyclitols in plants. In addition, it addresses the application of different methodologies utilized in the analysis of cyclitol compounds in plant.
Keywords:Cyclitols  D-pinitol  Extraction methods  Analytical methods
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