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Assignment of the human gene for phosphoglycolate phosphatase to chromosome 16 |
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| Authors: | R S Sparkes T Mohandas M C Sparkes M B Passage J D Shulkin |
| Institution: | (1) Division of Medical Genetics, Department of Medicine, UCLA Center for the Health Sciences, 90024 Los Angeles, CA, USA;(2) Department of Pediatrics, UCLA Center for the Health Sciences, 90024 Los Angeles, CA, USA;(3) Department of Psychiatry, UCLA Center for the Health Sciences, 90024 Los Angeles, CA, USA;(4) Division of Medical Genetics, Department of Pediatrics, Harbor-UCLA Medical Center, 1000 West Carson, 90509 Torrance, CA, USA |
| Abstract: | Summary Seventeen independently derived primary mouse-human hybrid clones were scored for the expression of human phosphoglycolate phosphatase (PGP) by electrophoresis and for the presence of human chromosomes with the aid of Q banding. The correlation of biochemical and cytogenetic analyses shows that the segregation of human PGP in these hybrids is concordant only with human chromosome 16, thus enabling the assignment of the genetic locus for PGP to human chromosome 16. |
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