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Microwave properties of cryoprotectants
Authors:Jeffrey D Macklis  Frederick D Ketterer  
Institution:1. Cryogenic Engineering Laboratory, Massachusetts Institute of Technology, Cambridge, Massachusetts U.S.A.;2. Harrison Department of Surgical Research and the Department of Electrical Engineering, University of Pennsylvania, Philadelphia, Pennsylvania U.S.A.
Abstract:The values of the dielectric constant and of the loss tangent for pure samples of DMSO, ethylene glycol, and glycerol were determined over the temperature range of + 15 to −70 °C. An operating frequency range of 1.45 to 1.55 GHz was used, allowing direct application of the results of both 0.915 and 2.450 GHz studies. Strong temperature dependencies were found, with peaks and irregularities occuring at subfreezing temperatures. In order to design a suitable cryoprotective system for the long term preservation of whole organs, the effect of cryoprotectant concentration on microwave properties must be known.
Keywords:Requests for reprints should be sent to Prof  F  D  Ketterer  Moore School of Electrical Engineering  200 S  33rd Street  Philadelphia  PA 19104  
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