应用基于内源信号的光学成像技术的视觉脑研究现状

基于脑内源信号的光学成像技术是近来国际上出现的一种脑功能成像方法。该技术既无毒，又具有较高的空间分辨率，因而被迅速应用于动物的视觉、听觉、体感皮层功能构筑的研究中。本文综述了这种光学脑功能成像在视觉脑研究方面所取得的重要进展，并分析了该方法与其他脑成像技术、微电极单细胞技术的关系。报道了国内自行研制第、套脑功能光学成像系统的研究工作，该系统已在猫初级视觉皮层不同深度获得了清晰的方位功能图，并已经和

PROGRESS IN VISUAL CORTICAL RESEARCH USING OPTICAL IMAGING BASED ON INTRINSIC SIGNALS

Optical imaging based on intrinsic signals is a newly emerged technique to detect the functional signals in the brain.Since it has no toxic effect and could provide a high spatial resolution it has been widely used in the functional architecture study of the visual,auditory and somatosensory cortex.In this paper,we introduced the recent progress on the vision research using this technique,and compared it with other brain functional imaging technique and single unit recording.We established the first optical imaging system in China.Using this system,the orientation map has been successfully recorded in the primary visual cortex in the cat at different depths,By now,a lot of work has been done with the system recently.