Sendai virus P gene produces multiple proteins from overlapping open reading frames |
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| Authors: | J Curran D Kolakofsky |
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| Affiliation: | Department of Microbiology, University of Geneva Medical School, Switzerland. |
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| Abstract: | The Sendai virus P gene contains overlapping open reading frames (ORFs), and several unusual mechanisms are used to produce multiple proteins from all three ORFs of this gene. These include the use of a non-AUG start codon, leaky ribosomal scanning, what appears to be scanning-independent ribosomal initiation and/or ribosomal jumping, and a form of mRNA editing. |
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