Intracellular trapping of cycloSal-pronucleotides by enzymatic cleavage |
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| Authors: | Jessen H J Tonn V Meier C |
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| Affiliation: | Department of Chemistry, Organic Chemistry, Faculty of Science, University of Hamburg, Martin-Luther-King-Platz, Hamburg, Germany. |
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| Abstract: | A new synthesis for cycloSal-pronucleotides bearing enzymatically cleavable triggers is presented. This trigger is introduced to trap the pronucleotide inside cells. The general concept and hydrolysis data in different media are discussed. |
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