Aminoglycoside antibiotics: inactivation by phosphorylation in Escherichia coli carrying R factors |
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Authors: | B Ozanne R Benveniste D Tipper J Davies |
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Abstract: | R-factor strains which are streptomycin-resistant and spectinomycin-sensitive have been found to inactivate streptomycin by a new mechanism. The 3'-OH group of the 2-deoxy-2-methylamino-l-glucopyranosyl moiety is phosphorylated. |
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